The Peter Attia Drive

Notable Guests

Matthew Walker 7x

Tom Dayspring 5x

Paul Conti 4x

Matt Kaeberlein 4x

Marty Makary 3x

Rhonda Patrick 3x

Peter Hotez 3x

Layne Norton 3x

Andy Galpin 2x

Ethan Weiss 2x

Jocko Willink 2x

Gerald Shulman 2x

David Allison 2x

Keith Flaherty 2x

Carol Tavris 2x

Recent Episodes

#399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.

Jul 13, 2026 · 01:56:48

Gayatri Devi

01:56:48

Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)

Jul 6, 2026 · 01:44:28

01:44:28

#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

Jun 29, 2026 · 09:56

09:56

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.

Jun 22, 2026 · 01:58:35

Renato Tomioka

01:58:35

#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy

Jun 15, 2026 · 50:23

50:23

#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.

Jun 8, 2026 · 01:40:57

Alzheimer's disease risk Brain lipidology: understanding APOE

01:40:57

#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements

Jun 1, 2026 · 54:50

54:50

#393 ‒ AMA #85: A guide to medications and supplements: determining what to take, what to skip, and how to know if they're working for you

May 25, 2026 · 13:06

13:06

#392 - Genetic testing: when it's valuable, how to choose the right test, and what to do with the results

May 18, 2026 · 01:02:25

01:02:25

#391 ‒ Colorectal cancer screening: importance of early screening, colonoscopy as a screening and preventive tool, and how to build a personalized strategy

May 11, 2026 · 07:35

✨ Colorectal cancer's suitability for early detection and prevention.

07:35

#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength training efficiency, dementia risk reduction, NAD supplements, and hydration

May 4, 2026 · 08:49

✨ Discusses building and interpreting family health history for personalized risk assessment.

Family health history dementia risk reduction preventing heart disease strength training efficiency

08:49

#389 - Thinking scientifically: why it's hard, why it matters, and a practical toolkit

Apr 27, 2026 · 53:59

✨ Explores the inherent human difficulty in scientific thinking due to cognitive biases.

a practical toolkit why it matters

53:59

#388 — Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives

Apr 20, 2026 · 46:21

✨ PSA is more informative when tracked over time, not as a single value.

46:21

#387 - AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field

Apr 13, 2026 · 22:01

✨ Peptides are marketed for muscle repair, longevity, and cosmetic enhancement.

AMA #83: Peptides

22:01

#386 - Aging clocks—what they measure, how they work, and their clinical and real-world relevance

Apr 6, 2026 · 42:45

✨ Aging clocks measure biological age using various biomarkers.

42:45

#385 - AMA #82: Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

Mar 23, 2026 · 18:52

✨ Discusses evolving health strategies across decades and managing chronic disease risk.

18:52

#384 - Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention

Mar 16, 2026 · 52:40

✨ Obicetrapib is a CETP inhibitor with cardiovascular benefits.

Special episode

52:40

#381 ‒ Alzheimer's disease in women: how hormonal transitions impact the female brain, the role of HRT, genetics, and lifestyle on risk, and emerging diagnostics and therapies | Lisa Mosconi, Ph.D.

Jan 26, 2026 · 02:06:34

✨ Exploring why Alzheimer's disproportionately affects women.

Lisa Mosconi

02:06:34

#380 ‒ The seed oil debate: are they uniquely harmful relative to other dietary fats? | Layne Norton, Ph.D.

Jan 19, 2026 · 02:07:42

✨ Debating if seed oils are uniquely harmful compared to other fats.

Layne Norton

02:07:42

#379 - AMA #79: A guide to cardiorespiratory training at any fitness level to improve healthspan, lifespan, and long-term independence

Jan 12, 2026 · 38:36

✨ Highlighting cardiorespiratory fitness as a predictor of longevity.

38:36

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Notable Guests

Recent Episodes

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