Notable Guests
MW
Matthew Walker
7x
TD
Tom Dayspring
5x
PC
Paul Conti
4x
MK
Matt Kaeberlein
4x
LN
Layne Norton
3x
AG
Andy Galpin
2x
GS
Gerald Shulman
2x
DS
David Sabatini
2x
KF
Keith Flaherty
2x
DA
David Allison
2x
Recent Episodes
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Discusses evolving health strategies across decades and managing chronic disease risk.
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Obicetrapib is a CETP inhibitor with cardiovascular benefits.
Special episode
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Exploring why Alzheimer's disproportionately affects women.
Lisa Mosconi
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Debating if seed oils are uniquely harmful compared to other fats.
Layne Norton
✨
Highlighting cardiorespiratory fitness as a predictor of longevity.
✨
Explaining how early exercise builds foundational health in girls.
Abbie Smith-Ryan
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Revealing key components of habit formation and the 'Four Laws of Behavioral Change'.
James Clear
✨
Synthesizes past interviews with Arthur Brooks on happiness.
Arthur Brooks
✨
Discusses key interventions for extending healthspan and lifespan.
✨
Explains nutritional vs. supplemental ketosis and achieving it.
Ketogenic diet
✨
Explores testosterone's role in male development and behavior.
Carole Hooven
✨
Shares insights on intentionality and embracing mortality.
Walter Green
✨
Explains thyroid hormone production and tissue-level regulation.
Antonio Bianco
✨
Details the impact of various fiber types on health.
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Explores drivers of desire, arousal, and orgasm in women.
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Defines lifespan, healthspan, and the marginal decade.
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Evaluates longevity drugs, aspirin, and muscle mass strategies.
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Current RDA for protein is insufficient; higher intake needed to maintain muscle mass, prevent frailty, and overcome anabolic resistance with aging and activity level
Rhonda Patrick
✨
RDA for protein originated from historical limitations and underestimates actual needs; evidence supports higher intake without harm concerns
David Allison
✨
Recent acetaminophen-autism headlines oversimplify multifactorial conditions; dramatic rise in autism diagnoses reflects expanded definitions and improved detection, not single causation