The Peter Attia Drive

Notable Guests

Matthew Walker 7x

Tom Dayspring 5x

Paul Conti 4x

Matt Kaeberlein 4x

Layne Norton 3x

Peter Hotez 3x

Rhonda Patrick 3x

Marty Makary 3x

Andy Galpin 2x

Ethan Weiss 2x

Jocko Willink 2x

Gerald Shulman 2x

Lloyd Klickstein 2x

Keith Flaherty 2x

David Allison 2x

Recent Episodes

#411 ‒ AMA #90: Strong convictions, loosely held: how Peter's views on fasting, keto, metformin, rapamycin, whole-body MRI, and exercise have changed

Oct 12, 2026 · 18:29

✨ Peter details evolving views on keto, fasting, and caloric restriction based on new evidence.

exercise have changed

18:29

#410 ‒ The biology of pregnancy: physiologic adaptation, gestational diabetes, preeclampsia, childbirth, and long-term maternal health | Kathryn Gray, M.D., Ph.D.

Oct 5, 2026 · 01:57:54

✨ Pregnancy involves significant cardiovascular, metabolic, and hormonal adaptations for mother and fetus.

Kathryn Gray

01:57:54

#409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles behind bringing new medicines to patients | Lloyd Klickstein, M.D., Ph.D.

Sep 28, 2026 · 02:26:26

✨ Dr. Klickstein details the drug development process from identifying unmet needs to therapeutic targets.

Lloyd Klickstein

02:26:26

#408 ‒ AMA #89: Thyroid health: interpreting symptoms, diagnosing and treating dysfunction, and navigating the gray zone

Sep 21, 2026 · 16:25

✨ Explains thyroid hormones T4, T3, TSH, and reverse T3, and their bodily functions.

Thyroid health: interpreting symptoms navigating the gray zone

16:25

#407 ‒ Preventing cardiovascular and Alzheimer's disease: lowering LDL early, APOE4, and promising new therapies | Michael Davidson, M.D.

Sep 14, 2026 · 01:59:22

✨ Dr. Davidson's family history inspired his focus on lipidology and primary prevention.

Michael Davidson

01:59:22

Blood pressure: how to measure, manage, and treat high blood pressure (AMA #48 rebroadcast)

Sep 7, 2026 · 01:16:50

✨ High blood pressure is common, often silent, and difficult to diagnose.

01:16:50

#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D.

Aug 31, 2026 · 01:55:46

✨ Dr. Grosberg differentiates primary and secondary headaches.

Brian Grosberg

01:55:46

#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease

Aug 24, 2026 · 39:23

✨ Liver health is a key indicator of metabolic dysfunction.

catch dysfunction early

39:23

#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D.

Aug 17, 2026 · 02:17:51

✨ Discussed hormones' role in mental health, challenging the neurotransmitter-only model.

Linus Abrams

02:17:51

#403 ‒ Peptides: separating scientific promise from marketing hype

Aug 10, 2026 · 53:22

✨ Peptides are marketed for recovery, muscle growth, longevity, and appearance.

53:22

#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.

Aug 3, 2026 · 02:25:14

✨ NMR blood analysis can assess heart disease, insulin resistance, inflammation, and mortality risk from one sample.

Jim Otvos

02:25:14

#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare

Jul 27, 2026 · 01:04:00

✨ Curiosity-driven research led to transformative drug classes.

01:04:00

#400 ‒ AMA #87: Environmental pollution and longevity: air pollution, noise, light, EMFs, and practical strategies to mitigate health risks

Jul 20, 2026 · 19:41

✨ Environmental pollution includes air, noise, and light, impacting longevity.

19:41

#399 ‒ The evolution of Alzheimer's disease and dementia care: how early detection, personalized treatment, new therapies, and a multimodal approach are changing the landscape | Gayatri Devi, M.D.

Jul 13, 2026 · 01:56:48

✨ Dementia is a spectrum; understanding Alzheimer's, vascular, Lewy body, and mixed types.

Gayatri Devi

01:56:48

Building strength and muscle mass: how to optimize training, nutrition, and more for longevity (AMA #71 rebroadcast)

Jul 6, 2026 · 01:44:28

✨ Distilled key insights on building strength and muscle mass for longevity.

01:44:28

#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

Jun 29, 2026 · 09:56

✨ Examined lean mass loss during GLP-1 RA treatment and compared it to other weight loss methods.

09:56

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.

Jun 22, 2026 · 01:58:35

✨ Explores endometriosis and adenomyosis diagnosis challenges.

Renato Tomioka

01:58:35

#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy

Jun 15, 2026 · 50:23

✨ Discusses breast cancer screening risks and recommendations.

50:23

#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.

Jun 8, 2026 · 01:40:57

✨ Dr. Tom Dayspring discusses lipids and brain health, focusing on cholesterol.

Alzheimer's disease risk Brain lipidology: understanding APOE

01:40:57

#394 ‒ Sleep pharmacology: the role of medications in healthy sleep, the promise of emerging therapies, and the evidence for common sleep supplements

Jun 1, 2026 · 54:50

✨ Sleep pharmacology: role of medications in healthy sleep.

54:50

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Notable Guests

Recent Episodes

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