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The Human Upgrade: Biohacking for Longevity & Performance
The Human Upgrade: Biohacking for Longevity & Performance

BONUS: The Anti-Aging Molecule Backed by Nobel Prize Research : 1492

Jun 28, 2026 · 00:12:25

About This Episode

<p>You already know something has changed - the energy crashes, the slow recovery, the brain fog that wasn't there ten years ago. Most people assume that's just aging. But it’s NOT. Nobel Prize-winning research has identified a single molecule that controls how fast your body breaks down, and more importantly, exactly why yours is being destroyed faster than it's being rebuilt. The fix isn't complicated, but the order you do it in matters. In this video, Dave breaks down what this molecule is, why your body is actively working against it, and the exact protocol (diet, fasting, exercise, and supplementation) to restore it before the gap gets any wider.</p><p><br /></p><p>Thank you to our sponsors!</p><ul><li>Gatlan | Book your free consultation at <a href="http://www.gatlan.com/DAVE" rel="noopener noreferrer" target="_blank">www.gatlan.com/DAVE</a></li><li>Viome | Check it out at <a href="http://viome.com/" rel="noopener noreferrer" target="_blank">viome.com</a> and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.</li><li>iRestore | Reverse hair loss at <a href="http://www.irestore.com/DAVE" rel="noopener noreferrer" target="_blank">www.irestore.com/DAVE</a> and get exclusive savings on the iRestore Elite, use code DAVE</li></ul><p><br /></p><p>Timestamps:</p><p>0:00 – The Longevity Switch</p><p>0:47 – Why Mitochondria Matter</p><p>2:28 – What Mitophagy Is</p><p>2:46 – How Mitophagy Works</p><p>4:18 – What Shuts It Off</p><p>8:54 – The Damage Compounds</p><p>9:22 – How to Turn It Back On</p><p>10:31 – Signal 1: Fasting</p><p>11:48 – Signal 2: Exercise (REHIT)</p><p>12:30 – Signal 3: Cold Exposure</p><p>13:22 – Signal 4: NAD+</p><p>14:29 – Signal 5: Urolithin A and Spermidine</p><p><br /></p><p>Connect with Dave Asprey!</p><p><br /></p><p>Website: https://daveasprey.com</p><p>TikTok: https://www.tiktok.com/@daveaspreyofficial</p><p>Instagram: https://www.instagram.com/dave.asprey/</p><p>Facebook: https://www.facebook.com/Daveaspreyofficial/</p><p>X: https://x.com/daveasprey</p><p>YouTube: https://www.youtube.com/c/daveaspreybpr</p><p><br /></p><p>The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/</p><p><br /></p><p>Danger Coffee: https://dangercoffee.com/DAVE15</p><p>Dave Asprey’s BEYOND Conference: https://beyondconference.com/</p><p>Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/</p><p>Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15</p><p>Upgrade Labs: https://upgradelabs.com</p><p>40 Years of Zen: https://40yearsofzen.com</p><p>See Privacy Policy at <a href="https://art19.com/privacy" rel="noopener noreferrer" target="_blank">https://art19.com/privacy</a> and California Privacy Notice at <a href="https://art19.com/privacy#do-not-sell-my-info" rel="noopener noreferrer" target="_blank">https://art19.com/privacy#do-not-sell-my-info</a>.</p>

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