Notable Guests
AM
Anjney Midha
2x
NL
Nathan Lambert
2x
AN
Akshay Nathan
1x
AL
Alex Lupsasca
1x
AV
Alex Volkov
1x
AG
Alex Graveley
1x
AE
Alexander Embiricos
1x
AT
Ali Taha
1x
AP
Alistair Pullen
1x
AS
Aman Sanger
1x
AA
Anastasios Angelopoulos
1x
AH
Andrew Hsu
1x
AW
Andrew White
1x
Recent Episodes
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AlphaFold's success was a starting point, not the end of protein folding.
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Periodic Labs is a leading AI scientist lab with rapid autonomous lab progress.
Ekin Dogus Cubuk
Liam Fedus
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Alex Zhang from MIT discusses academic ambition and emerging PhD talent.
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Dwarkesh's framing question on RLHF upset Computer Use proponents.
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Anthropic discusses their latest AI advancements and upcoming product launches.
Thariq Shihipar
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OpenRouter's journey from early open-weight models to a neutral routing layer.
Alex Atallah
Anjney Midha
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Runway's GWM Worlds 2 enables real-time interactive simulation from video/audio.
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AI models can be used for both offense and defense in bio-security.
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John Platt discusses AI's role in scientific discovery, mentioning his Oscar and named asteroids.
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Diogo Almeida critiques current frontier models, arguing they've taken the wrong path.
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AIUC announced $40M series A funding for their AI agent standard.
Rune Kvist
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Richard Socher discusses AI's impact on finance.
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Anima Anandkumar discusses building an AI weather model, FourCastNet.
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Simile AI raised $2B Series B for SimGym, a platform for AI simulations.
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Chai Discovery, a two-year-old AI company, is at the center of recent AI x Pharma deals.
Chai Discovery
Matthew McPartlon
Neil Patil
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Baseten raised $13B, becoming an AI Infra decacorn during the Inference Inflection.
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Codex usage exploded, reaching 10M users combined with ChatGPT Work.
Akshay Nathan
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Poolside AI releases Laguna S 2.1, outperforming larger models.
Eiso Kant
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Xaira's X-Cell model uses causal data for drug discovery.
Bo Wang
Ci Chu
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Lila Sciences envisions AI-driven labs resembling data centers for 24/7 experimentation.