Episodes (Page 2)
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Karpathy discusses AI agents designing experiments and improving autonomously.
From Coder to Manager: Navigating the Shift to Agentic Engineering with Notion Co-Founder Simon Last
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Notion's AI agents autonomously build integrations and write code for tasks.
Notion Co
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AI capital expenditure projected to reach $700 billion by end of 2026.
Neil Tiwari
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Rivian CEO RJ Scaringe details the shift to AI architecture.
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David Baszucki discusses how Roblox Studio is adopting industry-standard coding practices for developers
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CEO David Baszucki explains how improved infrastructure is changing creator behavior on Roblox
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Roblox is using AI to build photorealistic worlds with real-time physics simulation and acoustic modeling supporting thousands of simultaneous users
CEO David Baszucki
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Organ preservation time limits present a clear, measurable challenge in transplantation medicine
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Laura Deming explores how medical hibernation could freeze the body to wait for treatment availability
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Laura Deming questions how much of aging science is biology versus inherited assumptions and habit
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Medical hibernation raises social and philosophical questions beyond pure technological capability
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Until Labs is developing reversible cryopreservation technology to pause biological time, starting with organ transplants and scaling to full-body hibernation
Laura Deming
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OpenAI's open source model raises the commodity bar and makes AI adoption significantly easier
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Framing software as a 'tool' positions it as disposable and replaceable in customer perception
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AI-first software requires more than just architectural advantages to compete effectively
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Software stacks are continuously redefined as technology shifts from internet to mobile to AI eras
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Only a handful of companies worldwide achieve $10+ billion in pure-play software revenue because products are replaceable but platforms endure
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Ilya Sutskever identifies capable, autonomously reproducing AI as the scariest AI scenario
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Open source models give builders control over how AI systems are deployed and used