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Y Combinator Startup Podcast

Y Combinator Startup Podcast

Y Combinator · Technology · EN-US

This podcast features Y Combinator partners and founders discussing the journey of building a startup, from initial idea to global scaling. Through real stories and practical advice, it offers insights into the challenges and successes of entrepreneurship. The show is geared towards aspiring and...

303
Episodes
90
Guests

Notable Guests

SS
Startup School 6x
OH
Office Hours 4x
Michael Seibel
Michael Seibel 4x
Tom Blomfield
Tom Blomfield 3x
MF
Main Function 3x
AE
Aaron Epstein 2x
Sam Altman
Sam Altman 2x
HT
Harj Taggar 2x
DB
Divya Bhat 2x
KH
Kevin Hale 2x
AC
Adora Cheung 2x
GR
Geoff Ralston 2x
CF
Camille Fournier 1x
CC
CEO of Convoy 1x
AH
Anu Hariharan 1x

Recent Episodes

Mar 31, 2026 · 00:31:23
Variance, a startup detecting fraud for Fortune 500s, raised $21 million Series A.
Karine Mellata
00:31:23
Mar 27, 2026 · 00:57:23
François Chollet explores building AGI from first principles, not just scaling.
00:57:23
Mar 20, 2026 · 00:13:07
Solugen combines biology and chemistry to reinvent chemical manufacturing.
00:13:07
Mar 16, 2026 · 00:39:32
Emergent's AI platform allows non-technical users to build production-ready software.
00:39:32
Mar 9, 2026 · 00:53:20
Max Hodak co-founded Neuralink and leads Science, focusing on BCIs.
00:53:20
Mar 6, 2026 · 00:37:26
Avoiding common pitfalls in no-code design tools.
Raphael Schaad
00:37:26
Feb 27, 2026 · 00:19:45
Poetiq uses recursive self-improvement for AI reasoning.
00:19:45
Feb 21, 2026 · 00:23:21
The AI agent economy is emerging with tools like OpenClaw.
00:23:21
Feb 17, 2026 · 00:50:10
Boris Cherny, creator of Claude Code, shares his journey.
Its Creator Boris Cherny
00:50:10
Feb 14, 2026 · 00:07:50
Startups win by automating internal functions, not just hiring faster.
00:07:50
Feb 7, 2026 · 00:22:35
Peter Steinberger created OpenClaw, a viral open-source AI assistant that runs locally and integrates with messaging apps to execute tasks like email, calendar, and workflow management
00:22:35
Feb 6, 2026 · 00:45:59
Calvin French-Owen, co-founder of Segment and former OpenAI Codex engineer, discusses why coding agents like Claude Code feel particularly powerful
00:45:59
Jan 14, 2026 · 00:05:41
YC partner Ankit Gupta introduces the concept of a Minimum Evolvable Product (MEP) that adapts to early customer needs, beyond just building an MVP
00:05:41
Jan 8, 2026 · 00:15:43
Stoke Space is developing fully reusable rockets that can launch, survive reentry, and fly repeatedly to revolutionize spaceflight economics
00:15:43
Dec 22, 2025 · 00:30:22
2025 marked a shift from chaotic AI development to buildable, practical AI applications
00:30:22
Dec 17, 2025 · 00:11:59
ARC-AGI is redefining AGI measurement by focusing on reasoning, generalization, and adaptability instead of scale or memorization
00:11:59
Dec 12, 2025 · 00:42:19
Ryo Lu transformed Cursor from a VS Code feature layer into a leading AI code editor through rapid prototyping and iteration
00:42:19
Dec 10, 2025 · 00:38:46
James Hawkins built PostHog from a pre-YC deadline hack into a $1.4 billion unicorn in just a few years
00:38:46
Nov 28, 2025 · 00:39:35
Michael Mignano created Anchor to make podcast production accessible to millions through simple tap-based creation
00:39:35
Nov 20, 2025 · 00:35:34
Ryo Lu, Cursor's Head of Design, demonstrates how great product websites communicate what companies do through structure and clarity
00:35:34

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